1. Third Party Observations under Article 115 of EPC

TKDL third party submission under Article 115 EPC brought to the notice of examination division the prior art references on the use of Punica granatum (Pomegranate), Matricaria chamomilla (German chamomile), licorice(Glycyrrhiza glabra), Phyllanthus emblica (Aamla) and Myristica fragrans(nutmeg tree) have been used along with other ingredients for the treatment of acne and as complexion promoting agents from the books namely Qaraabaadeen Azam wa Akmal by Mohammad Akmal Khan (Unani, Exhibit 1), Qaraabaadeen Azam wa Akmal by Mohammad Akmal Khan (Unani, Exhibit 2), Vrndamadhava by Madhavah (Ayurveda, Exhibit 3), Cakradattah by Cakrapanidattah (Ayurveda, Exhibit 4), Yogaratnakarah - Commentary by Laksmipatisastri (Ayurveda, Exhibit 5), Vrndamadhava by Madhavah (Ayurveda, Exhibit 6) and Kaiyadevanighantau by Kaiyadeva (Ayurveda, Exhibit 7)

2. Relevant extract of EPO Examination Report

EPO Patent Examiner(s) took cognizance of TKDL references. Extract of examination report at Para 3 are reproduced below:

“A third party observation in accordance with Article 115 EPC has been filed. The documents furnished with the third party disclose the use of Punica granatum (comprising ellagic acid), Matricaria chamomilla (from which chamomile oil is obtained), licorice, Phyllanthus emblica (comprising gallic acid) and nutmeg have been traditionally used for the treatment of acne. This disclosure appears to be relevant for the assessment of inventive step under Art.56 EPC.”

Full examination report can be referred at EP1863507.pdf

3. Outcome of Third Party Observation and Examination Report

As the outcome of TKDL third party and other documents cited in examination report the examination is in progress and reply is awaited from the Applicant M/s REVANCE THERAPEUTICS INC, USA.